\u30c8\u30ea\u30c1\u30a6\u30e0 3<\/sup>H \u306e\u534a\u6e1b\u671f\u306f12.32 years\u30021\u5e74\u3092\u5206\u3067\u8868\u308f\u3059\u3068525,600<\/a>\u5206\uff08365\u65e5\u3067\u8a08\u7b97\uff09\u3002\u79d2\u3067\u8868\u308f\u3059\u306831,556,736\u79d2\uff08365.24\u65e5\u3067\u8a08\u7b97\uff09\u300212.32\u5e74\u306f388,778,987\u79d2\u3002<\/span><\/p>\n\n\n\n \u6642\u9593 t<\/em> = 0\u306e\u6642\u306e\u539f\u5b50\u6570\u3092N<\/em>0<\/sub>\u3068\u3059\u308b\u30681\u79d2\u5f8c\u306e\u539f\u5b50\u6570N<\/em>\u306f<\/p>\n\n\n\n \\[ N = N_0 \\left(\\frac{1}{2}\\right)^\\frac{1}{388778987} \\] 1\u79d2\u9593\u306b\u5d29\u58ca\u3057\u305f\u539f\u5b50\u6570N’ (Bq) \u306f \\[ N’ = N_0 \\times \\left(1 – \\left(\\frac{1}{2}\\right)^\\frac{1}{388778987}\\right) \\] N<\/em>0<\/sub>\u306b\u30a2\u30dc\u30ac\u30c9\u30ed\u5b9a\u65706.02214 \u00d7 1023<\/sup> mol\u22121<\/sup>\u3092\u4ee3\u5165\u3059\u308b\u3002 \\[ N’ = 6.02214 \\times 10^{23} \\times \\left(1 – \\left(\\frac{1}{2}\\right)^\\frac{1}{388778987}\\right) \\simeq 1.07367685 \\times 10^{15} \\mathrm{Bq\\,\\, mol}^{-1} \\] 1 Ci = 3.7 \u00d7 1010<\/sup> Bq\u306a\u306e\u3067\u3001 \\[ 1.07367685 \\times 10^{15}\\,\\,\\mathrm{Bq\\,\\, mol}^{-1} \\simeq 29018.29 \\,\\,\\mathrm{Ci\\,\\, mol}^{-1} \\simeq 29.02 \\,\\,\\mathrm{Ci\\,\\, mmol}^{-1} \\]\n\n\n\n 3<\/sup>H\u304c\u5d29\u58ca\u3057\u305f\u5f8c\u3001\u6a19\u8b58\u5316\u5408\u7269\u306fPKC\u3078\u306e\u7d50\u5408\u6d3b\u6027\u3092\u5b8c\u5168\u306b\u5931\u3046\u3068\u4eee\u5b9a\u3059\u308b\u3002<\/p>\n\n\n\n \u8cfc\u5165\u3057\u305f [3<\/sup>H]PDBu \u306e\u6bd4\u6d3b\u6027\u304c 17.16 Ci mmol-1<\/sup>\u3060\u3063\u305f\u306e\u3067\u3001\u3053\u306e\u8a66\u6599\u306f\u6a19\u8b58\u3055\u308c\u305f\u5316\u5408\u7269\u304c59.13%\u3001\u975e\u6a19\u8b58\u5316\u5408\u7269\u304c40.87%\u542b\u307e\u308c\u3066\u3044\u308b\u3002 \u6bd4\u6d3b\u6027\u304c\u3069\u306e\u3088\u3046\u306b\u5909\u5316\u3057\u3066\u3044\u304f\u304b\u8a08\u7b97\u3057\u3066\u307f\u305f\u3002<\/p>\n\n\n\n \u304a\u307e\u3051: \u653e\u5c04\u6027\u540c\u4f4d\u4f53\u6a19\u8b58\u5316\u5408\u7269\u304c\u5d29\u58ca\u5f8c\u306b\u3069\u306e\u3088\u3046\u306b\u306a\u308b\u304b\u8abf\u3079\u3066\u307f\u305f\u304c\u3088\u304f\u5206\u304b\u3089\u306a\u304b\u3063\u305f\u3002\u967d\u96fb\u5b50\u3092\u653e\u51fa\u3059\u308bfluorodeoxyglucose (18<\/sup>F) \u306e\u5834\u5408\u306f\u81ea\u5df1\u653e\u5c04\u5206\u89e3 (autoradiolysis) \u306b\u3088\u3063\u3066glucuronic acid\u3001arabonic acid\u3001araburonic acid\u3001gluconic acid\u3001arabinose\u3068\u3044\u3063\u305f\u9178\u5316\u751f\u6210\u7269\u304c\u5f62\u6210\u3055\u308c\u308b\u3089\u3057\u30441)<\/sup>\u3002[3<\/sup>H]PDBu\u306e\u03b2\u5d29\u58ca\u5f8c\u306e\u5909\u5316\u306e\u4e88\u60f3\u56f3\u3092\u4e0b\u306e\u3088\u3046\u306b\u66f8\u3044\u3066\u307f\u305f\u304c\u3001\u3042\u304f\u307e\u3067\u4e88\u60f3\u3002<\/p>\n\n\n\n <\/p>\n\n\n\n 1) B\u00fariov\u00e1, E., Mac\u00e1\u0161ek, F., Melichar, F. et al.<\/i> Autoradiolysis of the 2-deoxy-2-[18<\/sup>F]fluoro-D-glucose radiopharmaceutical. J. Radioanal. Nucl. Chem. <\/i>2005<\/strong>, 264<\/em>, 595\u2013602. https:\/\/doi.org\/10.1007\/s10967-005-0759-9<\/a><\/p>\n\n\n\n (\u4e86)<\/p>\n","protected":false},"excerpt":{"rendered":" \u7814\u7a76\u5ba4\u7528\u30e1\u30e2\uff082026\u5e7410\u670810\u65e5\u6539\u8a02\uff09 \u95a2\u9023\u8a18\u4e8b: \u7d50\u5408 …<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_locale":"ja","_original_post":"https:\/\/www.ag.kagawa-u.ac.jp\/charlesy\/?p=2558","footnotes":""},"categories":[9],"tags":[],"class_list":["post-2558","post","type-post","status-publish","format-standard","hentry","category-9","ja"],"aioseo_notices":[],"aioseo_head":"\n\t\t\n\t\n\t\n\t\n\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n\t\t\n
year<\/td> % remained<\/td> labelled\/unlabelled<\/td> \u6bd4\u6d3b\u6027 (Ci mmol\u22121<\/sup>)<\/td> \u30e2\u30eb\u6fc3\u5ea6 (\u03bcM)<\/td><\/tr> 0 (2013)<\/td> 100.00%<\/td> 59.13 : 40.87<\/td> 17.16<\/td> 5.300<\/td><\/tr> 1 (2014)<\/td> 94.53%<\/td> 55.90 : 40.87<\/td> 16.76<\/td> 5.129<\/td><\/tr> 2 (2015)<\/td> 89.36%<\/td> 52.84 : 40.87<\/td> 16.36<\/td> 4.966<\/td><\/tr> 3 (2016)<\/td> 84.47%<\/td> 49.95 : 40.87<\/td> 15.96<\/td> 4.813<\/td><\/tr> 4 (2017)<\/td> 79.85%<\/td> 47.21 : 40.87<\/td> 15.56<\/td> 4.668<\/td><\/tr> 5 (2018)<\/td> 75.48%<\/td> 44.63 : 40.87<\/td> 15.15<\/td> 4.532<\/td><\/tr> 6 (2019)<\/td> 71.35%<\/td> 42.19 : 40.87<\/td> 14.74<\/td> 4.402<\/td><\/tr> 7 (2020)<\/td> 67.45%<\/td> 39.88 : 40.87<\/td> 14.33<\/td> 4.280<\/td><\/tr> 8 (2021)<\/td> 63.76%<\/td> 37.70 : 40.87<\/td> 13.92<\/td> 4.164<\/td><\/tr> 9 (2022)<\/td> 60.27%<\/td> 35.64 : 40.87<\/td> 13.52<\/td> 4.055<\/td><\/tr> 10 (2023)<\/td> 56.97%<\/td> 33.69 : 40.87<\/td> 13.11<\/td> 3.952<\/td><\/tr> 11 (2024)<\/td> 53.85%<\/td> 31.84 : 40.87<\/td> 12.71<\/td> 3.854<\/td><\/tr> 12 (2025)<\/td> 50.91%<\/td> 30.10 : 40.87<\/td> 12.31<\/td> 3.762<\/td><\/tr> 13 (2026)<\/td> 48.12%<\/td> 28.46 : 40.87<\/td> 11.91<\/td> 3.672<\/td><\/tr> 14\uff082027\uff09<\/td> 45.49%<\/td> 26.90 : 40.87<\/td> 11.52<\/td> 3.592<\/td><\/tr> 15\uff082028\uff09<\/td> 43.00%<\/td> 25.43 : 40.87<\/td> 11.13<\/td> 3.514<\/td><\/tr> 16\uff082029\uff09<\/td> 40.65%<\/td> 24.04 : 40.87<\/td> 10.75<\/td> 3.440<\/td><\/tr> 17\uff082030\uff09<\/td> 38.43%<\/td> 22.72 : 40.87<\/td> 10.37<\/td> 3.370<\/td><\/tr> 18\uff082031\uff09<\/td> 36.32%<\/td> 21.48 : 40.87<\/td> 10.00<\/td> 3.304<\/td><\/tr> 19\uff082032\uff09<\/td> 34.34%<\/td> 20.30 : 40.87<\/td> 9.63<\/td> 3.242<\/td><\/tr> 20\uff082033\uff09<\/td> 32.46%<\/td> 19.19 : 40.87<\/td> 9.27<\/td> 3.183<\/td><\/tr> 21\uff082034\uff09<\/td> 30.68%<\/td> 18.14 : 40.87<\/td> 8.92<\/td> 3.128<\/td><\/tr> 22\uff082035\uff09<\/td> 29.00%<\/td> 17.15 : 40.87<\/td> 8.58<\/td> 3.075<\/td><\/tr><\/tbody><\/table><\/figure>\n\n\n\n ![\"\"](\"https:\/\/www.ag.kagawa-u.ac.jp\/charlesy\/wp\/wp-content\/uploads\/2021\/02\/beta_decay-300x166.png\")
<\/figure>\n\n\n\n