{"id":736,"date":"2024-11-15T12:53:54","date_gmt":"2024-11-15T03:53:54","guid":{"rendered":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/?page_id=736"},"modified":"2026-10-08T13:30:49","modified_gmt":"2026-10-08T04:30:49","slug":"english","status":"publish","type":"page","link":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/english\/","title":{"rendered":"English page"},"content":{"rendered":"\n<h4 class=\"wp-block-heading alignwide has-system-font-font-family\"><strong>About us<\/strong><\/h4>\n\n\n\n<h6 class=\"wp-block-heading alignwide\" style=\"text-transform:none\">\u3000Secondary metabolites produced by plants and microorganisms exhibit diverse chemical structures and a wide range of biological activities that arise from this structural diversity. Therefore, many secondary metabolites (natural products) have been used as medicines, pesticides or drug candidates. <br>\u3000In our laboratory, we aim to discover new natural products, novel medicinal seeds, and new agrochemical seeds by integrating the following four research pillars.<br><br><strong>1. Development of screening systems for pharmaceutical and agricultural research<\/strong><br><strong>2. Development of methods to activate cryptic or silent gene clusters in microorganisms<\/strong><br><strong>3. Search for new natural products and bioactive compounds from collections of our plants and microorganisms, as well as from pathogenic microorganisms including <em>Nocardia<\/em><\/strong><br><strong>4. Elucidation of the molecular mechanisms of new bioactive natural products and analysis of the biosynthetic gene clusters responsible for the production of new natural products<\/strong><br>\u3000<br>\u3000Students in our laboratory are expected to grow as researchers with perspectives in both organic chemistry and biological sciences through their research activities.<\/h6>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1202\" src=\"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.1-English-scaled.jpg\" alt=\"\" class=\"wp-image-1206\" srcset=\"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.1-English-scaled.jpg 2560w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.1-English-300x141.jpg 300w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.1-English-1024x481.jpg 1024w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.1-English-768x361.jpg 768w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.1-English-1536x721.jpg 1536w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.1-English-2048x962.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><figcaption class=\"wp-element-caption\"><strong>Fig.1 Development of methods to activate cryptic or silent gene clusters in microorganisms<\/strong><\/figcaption><\/figure>\n\n\n\n<p class=\"wp-block-paragraph\"><\/p>\n\n\n\n<figure class=\"wp-block-image size-full\"><img loading=\"lazy\" decoding=\"async\" width=\"2560\" height=\"1942\" src=\"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.2-English-scaled.jpg\" alt=\"\" class=\"wp-image-1207\" srcset=\"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.2-English-scaled.jpg 2560w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.2-English-300x228.jpg 300w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.2-English-1024x777.jpg 1024w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.2-English-768x583.jpg 768w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.2-English-1536x1165.jpg 1536w, https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-content\/uploads\/2025\/10\/Fig.2-English-2048x1554.jpg 2048w\" sizes=\"auto, (max-width: 2560px) 100vw, 2560px\" \/><figcaption class=\"wp-element-caption\"><strong>Fig.2 Isolated new natural products and their functional analysis<\/strong><\/figcaption><\/figure>\n\n\n\n<h4 class=\"wp-block-heading alignwide has-system-font-font-family\"><strong>Members<\/strong><\/h4>\n\n\n\n<h6 class=\"wp-block-heading alignwide\" style=\"text-transform:none\"><strong>\u30fbFaculty member<\/strong><br>\u3000Assist. Prof.<br>\u3000<strong>Yasumasa Hara, Ph.D.<\/strong><br>\u3000<a href=\"https:\/\/orcid.org\/0000-0003-0451-8731\">ORCiD<\/a>, <a href=\"https:\/\/researchmap.jp\/10824625\">researchmap<\/a><br><br>\u30fb<strong>Students<\/strong><br>\u3000-graduate-<br>\u3000<em>2nd year master&#8217;s student<\/em><br>\u3000\u3000Yuka Tarui<br>\u3000\u3000Tsubasa Horiuchi<br>\u3000\u3000Miu Mori<br>\u3000<br>\u3000<em>1st year master&#8217;s student<\/em><br>\u3000\u3000Bui Cong Tri<br>\u3000\u3000Ai Kanagawa<br>\u3000\u3000Mio Kuwahara<br>\u3000\u3000So Yoshida<br><br>\u3000-undergraduate-<br>\u3000<em>4th year student<\/em><br>\u3000\u3000Yume Okawa<br>\u3000\u3000Mao Kameda<br>\u3000\u3000Riko Nakasone<br>\u3000<br>\u3000<em>3rd year student<\/em><br>\u3000\u3000Momoka Ikeda<br>\u3000\u3000Yuki Uchida<br>\u3000\u3000Honoka Shimadzu\u3000\u3000<br><br><\/h6>\n\n\n\n<h4 class=\"wp-block-heading alignwide has-system-font-font-family\"><strong>Publications<\/strong><\/h4>\n\n\n\n<h6 class=\"wp-block-heading alignwide\" style=\"text-transform:none\">Please see <a href=\"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/%e7%a0%94%e7%a9%b6%e6%a5%ad%e7%b8%be\/\" data-type=\"page\" data-id=\"136\">this page<\/a><br><\/h6>\n\n\n\n<h4 class=\"wp-block-heading alignwide has-system-font-font-family\"><strong>Recruitment<\/strong><\/h4>\n\n\n\n<h6 class=\"wp-block-heading alignwide\" style=\"text-transform:none\">\u3000We welcome applications and inquiries from undergraduate students in Japan, students seeking admission to our graduate program from Japan and abroad, and postdoctoral researchers. Our research focuses on the discovery of natural products from plants and microorganisms, including studies of their chemical structures and biological activities, as well as culture-based approaches to natural product discovery using microbial interactions.<br>\u3000<strong>Undergraduate students at Kagawa University seeking placement in our laboratory<\/strong> should have a strong interest in natural product research and a willingness to learn experimental techniques in natural product chemistry. Prior research experience in natural product chemistry is not required.<br>\u3000<strong>Students seeking admission to our graduate program and wishing to join our laboratory<\/strong> should have research experience in natural product chemistry. Prior experience in the isolation and structural elucidation of natural products is particularly desirable.<br>\u3000<strong>All students, including those applying from outside Japan, are required to have sufficient Japanese language proficiency for routine communication and research activities in the laboratory (approximately JLPT N3 level or higher)<\/strong>. Applicants from outside Japan who wish to pursue graduate studies in our laboratory should first review<a href=\"https:\/\/www.ag.kagawa-u.ac.jp\/english\/\"> the graduate admissions information provided by Kagawa University<\/a> and the information on t<a href=\"https:\/\/www.ag.kagawa-u.ac.jp\/afs_network\/en\/\">he Special Master\u2019s Program in Sustainable Food Production and Management<\/a>.<br>\u3000<strong>Postdoctoral researchers<\/strong> should have a strong background in natural product research, particularly in the isolation and structural elucidation of natural products, and should be able to independently pursue their research. Postdoctoral researchers are expected to have independent fellowship support.<br>\u3000If you are interested in our research, please feel free to contact us by email.<br><br><strong>Contact to<\/strong><br>\u3000Assist. Prof. Yasumasa HARA<br>\u3000hara.yasumasa[at]kagawa-u.ac.jp<br>\u3000\u3000Please send e-mail replacing [at] with @.<\/h6>\n","protected":false},"excerpt":{"rendered":"<p>About us \u3000Secondary metabolites produced by plants and microorganisms exhibit diverse chemical structures and  [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"parent":0,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_themeisle_gutenberg_block_has_review":false,"footnotes":""},"class_list":["post-736","page","type-page","status-publish","hentry"],"_links":{"self":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-json\/wp\/v2\/pages\/736","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-json\/wp\/v2\/pages"}],"about":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-json\/wp\/v2\/types\/page"}],"author":[{"embeddable":true,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-json\/wp\/v2\/comments?post=736"}],"version-history":[{"count":32,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-json\/wp\/v2\/pages\/736\/revisions"}],"predecessor-version":[{"id":1774,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-json\/wp\/v2\/pages\/736\/revisions\/1774"}],"wp:attachment":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/hara\/wp-json\/wp\/v2\/media?parent=736"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}