{"id":17679,"date":"2016-12-15T16:58:09","date_gmt":"2016-12-15T07:58:09","guid":{"rendered":"http:\/\/www.ag.kagawa-u.ac.jp?post_type=research&p=17679"},"modified":"2024-05-09T10:34:27","modified_gmt":"2024-05-09T01:34:27","slug":"%e6%9c%9b%e6%9c%88%e3%80%80%e9%80%b2","status":"publish","type":"research","link":"https:\/\/www.ag.kagawa-u.ac.jp\/?research=%e6%9c%9b%e6%9c%88%e3%80%80%e9%80%b2","title":{"rendered":"\u671b\u6708 \u9032\uff08\u517c\uff09"},"content":{"rendered":"
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\u65e5\u672c\u8a9e<\/div><\/div>
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English<\/div><\/div><\/div><\/div>\n
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\u9818\u57df\u540d\u3000\u3000  \u690d\u7269\u79d1\u5b66<\/mark><\/strong><\/h2>\n\n\n\n

\u6559\u54e1\u6c0f\u540d  \u671b\u3000\u6708\u3000\u3000\u9032<\/mark><\/strong><\/h2>\n<\/div>\n\n\n\n
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\u7814\u7a76\u5206\u91ce\u3000\u5e0c\u5c11\u7cd6\u907a\u4f1d\u5b50\u5de5\u5b66<\/mark><\/strong><\/h2>\n<\/div>\n<\/div>\n\n\n\n
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\u7814\u7a76\u30ad\u30fc\u30ef\u30fc\u30c9\uff1a\u5e0c\u5c11\u7cd6\uff0c\u907a\u4f1d\u5b50\uff0c\u690d\u7269\uff0c\u5fae\u751f\u7269\uff0c\u690d\u7269-\u5fae\u751f\u7269\u9593\u76f8\u4e92\u4f5c\u7528<\/strong><\/p>\n<\/div>\n\n\n\n

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\u3000\u6700\u8fd1\u306e\u7814\u7a76\u8ab2\u984c<\/strong><\/h2>\n\n\n\n

\uff11\uff0e\u5e0c\u5c11\u7cd6\u751f\u7523\u907a\u4f1d\u5b50\u306b\u95a2\u3059\u308b\u7814\u7a76\u3000<\/strong><\/h2>\n\n\n\n

\u3000\u3053\u308c\u307e\u3067\u306b\u9999\u5ddd\u5927\u5b66\u3067\u306f\u3001Izumoring\u6226\u7565\u306b\u3088\u308b\u5404\u7a2e\u306e\u5e0c\u5c11\u7cd6\u5909\u63db\u9175\u7d20\u306e\u5358\u96e2\u3092\u884c\u3044\u3001\u91cf\u7523\u5316\u304c\u958b\u59cb\u3055\u308c\u305fD-\u30d7\u30b7\u30b3\u30fc\u30b9\u3092\u521d\u3081\u3068\u3059\u308b\u5168\u3066\u306e\u5e0c\u5c11\u7cd6\u751f\u7523\u3092\u53ef\u80fd\u306b\u3057\u3066\u304d\u305f\u3002\u6211\u3005\u306e\u7814\u7a76\u5ba4\u3067\u306f\u3001\u5fae\u751f\u7269\u3084\u690d\u7269\u304b\u3089\u5e0c\u5c11\u7cd6\u751f\u7523\u9175\u7d20\u907a\u4f1d\u5b50\u8cc7\u6e90\u3092\u767a\u6398\u3059\u308b\u3068\u3068\u3082\u306b\u3001\u751f\u7523\u9175\u7d20\u306e\u6a5f\u80fd\u3092\u89e3\u6790\u30fb\u6539\u826f\u3059\u308b\u3053\u3068\u306b\u3088\u3063\u3066\u3001\u3042\u3089\u3086\u308b\u5e0c\u5c11\u7cd6\u306e\u9ad8\u52b9\u7387\u3067\u8fc5\u901f\u306a\u751f\u7523\u3092\u76ee\u6307\u3057\u3066\u3044\u308b\u3002<\/p>\n<\/div>\n\n\n\n

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\uff12\uff0e\u5e0c\u5c11\u7cd6\u4f5c\u7528\u30e1\u30ab\u30cb\u30ba\u30e0\u306b\u95a2\u3059\u308b\u7814\u7a76<\/strong><\/h2>\n\n\n\n

\u3000<\/strong>\u5e0c\u5c11\u7cd6\u306f\u9999\u5ddd\u5927\u5b66\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u5404\u7a2e\u7814\u7a76\u306b\u3088\u308a\u3001\u98df\u54c1\u3001\u533b\u85ac\u3001\u8fb2\u85ac\u3068\u5404\u65b9\u9762\u3078\u306e\u666e\u53ca\u52b9\u679c\u304c\u671f\u5f85\u3055\u308c\u3066\u3044\u308b\u3002\u4e00\u65b9\u3067\u3001\u5e0c\u5c11\u7cd6\u306e\u4f5c\u7528\u6a5f\u4f5c\u306b\u95a2\u3059\u308b\u7814\u7a76\u306f\u307e\u3060\u5c11\u306a\u3044\u3002\u5e0c\u5c11\u7cd6\u306e\u69d8\u3005\u306a\u5206\u91ce\u3078\u306e\u6709\u52b9\u6d3b\u7528\u3092\u4fc3\u9032\u3059\u308b\u305f\u3081\u306b\u3001\u690d\u7269\u3084\u5fae\u751f\u7269\u3092\u7814\u7a76\u6750\u6599\u3068\u3057\u3066\u3001\u5e0c\u5c11\u7cd6\u4f5c\u7528\u3001\u7279\u306b\u5e0c\u5c11\u7cd6\u306e\u30ea\u30f3\u9178\u5316\u3068\u4ee3\u8b1d\u306b\u95a2\u3059\u308b\u7814\u7a76\u3092\u884c\u3063\u3066\u3044\u308b\u3002<\/p>\n<\/div>\n\n\n\n

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\uff13\uff0e\u690d\u7269-\u5fae\u751f\u7269\u9593\u76f8\u4e92\u4f5c\u7528\u6642\u306b\u6a5f\u80fd\u3059\u308b\u907a\u4f1d\u5b50\u306e\u89e3\u6790<\/strong><\/h2>\n\n\n\n

\u3000<\/strong>\u5fae\u751f\u7269\u306f\u7cd6\u3092\u5909\u63db\u3059\u308b\u80fd\u529b\u3092\u6301\u3061\u3001\u690d\u7269\u306f\u7cd6\u3092\u84c4\u7a4d\u3059\u308b\u80fd\u529b\u3092\u6301\u3064\u3002\u305d\u306e\u5883\u754c\u9818\u57df\u3067\u3042\u308b\u690d\u7269-\u5fae\u751f\u7269\u9593\u76f8\u4e92\u4f5c\u7528\u306e\u5834\u3067\u306f\u591a\u69d8\u306a\u5fdc\u7b54\u304c\u8d77\u3053\u308a\u3001\u4e00\u6b21\u4ee3\u8b1d\u3084\u4e8c\u6b21\u4ee3\u8b1d\u306b\u95a2\u4fc2\u3059\u308b\u591a\u304f\u306e\u907a\u4f1d\u5b50\u767a\u73fe\u304c\u5909\u52d5\u3057\u3066\u3044\u308b\u3053\u3068\u3082\u308f\u304b\u3063\u3066\u3044\u308b\u3002\u6211\u3005\u306e\u7814\u7a76\u5ba4\u3067\u306f\u3001\u30a4\u30cd\u3044\u3082\u3061\u75c5\u83cc\u3084Alternaria<\/em>\u5c5e\u83cc\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u690d\u7269\u75c5\u539f\u83cc\u611f\u67d3\u6642\u306e\u7cd6\u4ee3\u8b1d\u3092\u4e2d\u5fc3\u3068\u3057\u305f\u4ee3\u8b1d\u95a2\u9023\u907a\u4f1d\u5b50\u306e\u6a5f\u80fd\u89e3\u6790\u3092\u3001\u690d\u7269\u5074\u3001\u5fae\u751f\u7269\u5074\u306e\u4e21\u65b9\u306e\u8996\u70b9\u304b\u3089\u884c\u3063\u3066\u3044\u308b\u3002<\/p>\n<\/div>\n\n\n\n

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\u4ee3\u8868\u7684\u306a\u7814\u7a76\u696d\u7e3e<\/strong><\/p>\n<\/div>

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  • Nishimura, T., Mochizuki, S. et al<\/em>. (2016)  Magnaporthe oryzae <\/em>Glycine-Rich Secretion Protein, Rbf1 Critically Participates in Pathogenicity through the Focal Formation of the Biotrophic Interfacial Complex, PLOS Pathogens<\/em>, 12(10), e1005921.<\/li>\n\n\n\n
  • Mochizuki, S. et al<\/em>. (2015)  Live-cell imaging of rice cytological changes reveals the importance of host vacuole maintenance for biotrophic invasion by blast fungus, Magnaporthe oryzae<\/em>, MicrobiologyOpen<\/em>, 4(6), 952-966.<\/li>\n\n\n\n
  • Mochizuki, S. et al<\/em>. (2014)  Ubiquitin ligase EL5 maintains the viability of root meristems by influencing cytokinin-mediated nitrogen effects in rice, Journal of Experimental Botany<\/em>, 65(9), 2307-2318.<\/li>\n\n\n\n
  • Kouzai, Y. et al<\/em>. (2014)  Targeted Gene Disruption of OsCERK1<\/em> Reveals Its Indispensable Role in Chitin Perception and Involvement in the Peptidoglycan Response and Immunity in Rice, Molecular Plant-Microbe Interactions<\/em>, 27(9), 975-982.<\/li>\n\n\n\n
  • Sakai, T., Mochizuki, S. et al<\/em>. (2012) The WAVY GROWTH 3 E3 ligase family controls the gravitropic response in Arabidopsis roots, The Plant Journal<\/em>, 70, 303-314.<\/li>\n\n\n\n
  • Mochizuki, S. et al<\/em>. (2011)  Localization of probe-accessible chitin and characterization of genes encoding chitin-binding domains during rice\u2013Magnaporthe oryzae<\/em> interactions, Journal of General Plant Pathology<\/em>, 77, 163-173.<\/li>\n<\/ul>\n\n\n\n

    <\/p>\n\n<\/div>

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    Research Area: Plant Science<\/mark>
    Research Field: Rare sugar molecular biology<\/mark>
    Name: MOCHIZUKI, Susumu<\/mark><\/strong><\/h2>\n\n\n\n
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    Keywords:  Rare sugars, Genetic Functions, Plant biology,  Microbiology, Plant-Microbe interactions<\/strong><\/p>\n\n\n\n

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     Recent Research<\/strong><\/h2>\n\n\n\n

    1. Rare sugar production<\/strong><\/h2>\n\n\n\n

    Several sugar converting enzymes were isolated at Kagawa University using the Izumoring strategy. These enzymes made it possible to produce many types of rare sugars, including D-allulose. Prompted by the growing industrial potential of rare sugars, the present study aims to select the best enzymes for production of rare sugars, and to improve their production efficiency by using genetic engineering methods.<\/p>\n<\/div>\n\n\n\n

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    2. Functional mechanisms of rare sugars<\/strong><\/h2>\n\n\n\n

    These rare sugars can potentially be used for many applications, including in health food products, pharmaceutical products, and agricultural materials. However, the functional mechanisms of rare sugars have not yet been clarified. To gain a better understanding of how rare sugars act upon living cells, we are analyzing gene functions in sugar-treated plants and microbes.<\/p>\n<\/div>\n\n\n\n

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    3. Plant-microbe interaction<\/strong><\/h2>\n\n\n\n

    Microorganisms have the ability to produce these sugars, and plants are able to store them. Many primary and secondary metabolism-related genes function in both plants and microbes during their interaction. To understand sugar and sugar-related metabolisms in more detail, we are analyzing the functions of these genes during interactions between plants and plant pathogenic fungi (Magnaporthe<\/em> and Alternaria<\/em>).<\/p>\n<\/div>\n\n\n\n

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    Publications<\/strong><\/p>\n<\/div>

    \"\"<\/figure><\/div>\n\n\n\n
      \n
    • Nishimura, T., Mochizuki, S. et al<\/em>. (2016)  Magnaporthe oryzae <\/em>Glycine-Rich Secretion Protein, Rbf1 Critically Participates in Pathogenicity through the Focal Formation of the Biotrophic Interfacial Complex, PLOS Pathogens<\/em>, 12(10), e1005921.<\/li>\n\n\n\n
    • Mochizuki, S. et al<\/em>. (2015)  Live-cell imaging of rice cytological changes reveals the importance of host vacuole maintenance for biotrophic invasion by blast fungus, Magnaporthe oryzae<\/em>, MicrobiologyOpen<\/em>, 4(6), 952-966.<\/li>\n\n\n\n
    • Mochizuki, S. et al<\/em>. (2014)  Ubiquitin ligase EL5 maintains the viability of root meristems by influencing cytokinin-mediated nitrogen effects in rice, Journal of Experimental Botany<\/em>, 65(9), 2307-2318.<\/li>\n\n\n\n
    • Kouzai, Y. et al<\/em>. (2014)  Targeted Gene Disruption of OsCERK1<\/em> Reveals Its Indispensable Role in Chitin Perception and Involvement in the Peptidoglycan Response and Immunity in Rice, Molecular Plant-Microbe Interactions<\/em>, 27(9), 975-982.<\/li>\n\n\n\n
    • Sakai, T., Mochizuki, S. et al<\/em>. (2012) The WAVY GROWTH 3 E3 ligase family controls the gravitropic response in Arabidopsis roots, The Plant Journal<\/em>, 70, 303-314.<\/li>\n\n\n\n
    • Mochizuki, S. et al<\/em>. (2011)  Localization of probe-accessible chitin and characterization of genes encoding chitin-binding domains during rice\u2013Magnaporthe oryzae<\/em> interactions, Journal of General Plant Pathology<\/em>, 77, 163-173.<\/li>\n<\/ul>\n\n\n\n

      <\/p>\n\n<\/div><\/div>\n <\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":20300,"menu_order":0,"comment_status":"closed","ping_status":"closed","template":"","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","ub_ctt_via":"","footnotes":""},"class_list":["post-17679","research","type-research","status-publish","has-post-thumbnail","hentry","research_category-158","center_category-257","center_category-258","sdgs_category-6","sdgs_category-9","sdgs_category-17","sdgs_category-12","sdgs_category-18","sdgs_category-5"],"_links":{"self":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/research\/17679","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/research"}],"about":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/research"}],"author":[{"embeddable":true,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=17679"}],"version-history":[{"count":12,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/research\/17679\/revisions"}],"predecessor-version":[{"id":32706,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/research\/17679\/revisions\/32706"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/media\/20300"}],"wp:attachment":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=17679"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}