{"id":3479,"date":"2012-01-24T16:54:40","date_gmt":"2012-01-24T07:54:40","guid":{"rendered":"http:\/\/www.ag.kagawa-u.ac.jp?post_type=research&p=3479"},"modified":"2024-05-09T11:13:14","modified_gmt":"2024-05-09T02:13:14","slug":"%e6%9d%be%e5%b0%be-%e9%81%94%e5%8d%9a%e3%80%80%e6%a0%84%e9%a4%8a%e5%ad%a6","status":"publish","type":"research","link":"https:\/\/www.ag.kagawa-u.ac.jp\/?research=%e6%9d%be%e5%b0%be-%e9%81%94%e5%8d%9a%e3%80%80%e6%a0%84%e9%a4%8a%e5%ad%a6","title":{"rendered":"\u677e\u5c3e\u3000\u9054\u535a"},"content":{"rendered":"
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\u9818\u3000\u57df\u3000\u540d\u3000\u3000\u98df\u54c1\u79d1\u5b66<\/mark><\/strong><\/strong><\/h2>\n\n\n\n

\u6559\u54e1\u6c0f\u540d\u3000\u3000 \u677e \u5c3e \u9054 \u535a<\/mark><\/strong><\/h2>\n<\/div>\n\n\n\n
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\u7814\u7a76\u5206\u91ce\u3000\u98df\u54c1\u6804\u990a\u5b66<\/mark><\/strong><\/h2>\n<\/div>\n<\/div>\n\n\n\n
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\u6700\u8fd1\u306e\u7814\u7a76\u8ab2\u984c<\/strong><\/h2>\n\n\n\n

\uff11\uff0e\u5e0c\u5c11\u7cd6D-\u30d7\u30b7\u30b3\u30fc\u30b9\u304a\u3088\u3073\u5e0c\u5c11\u7cd6\u542b\u6709\u7570\u6027\u5316\u7cd6\u306e\u6a5f\u80fd\u6027\u306b\u95a2\u3059\u308b\u7814\u7a76<\/strong><\/h2>\n\n\n\n

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\uff12\uff0e\u7cd6\u8cea\u5236\u9650\u98df\uff08\u8d85\u4f4e\u7cd6\u8cea\u98df\uff09\u306e\u6709\u52b9\u6027\u306b\u95a2\u3059\u308b\u7814\u7a76<\/strong><\/h2>\n\n\n\n

\u3000\u8fd1\u5e74\u3001\u7cd6\u5c3f\u75c5\u306e\u98df\u4e8b\u7642\u6cd5\u3068\u3057\u3066\u7cd6\u8cea\u5236\u9650\u98df\u304c\u5404\u7a2e\u5a92\u4f53\u3092\u901a\u3058\u3066\u975e\u5e38\u306b\u8a71\u984c\u306b\u306a\u3063\u3066\u304a\u308a\u3001\u3059\u3067\u306b\u4e00\u90e8\u75c5\u9662\u306a\u3069\u3067\u63a1\u7528\u3055\u308c\u3066\u3044\u308b\u3002\u7cd6\u8cea\u5236\u9650\u98df\u306f\u7cd6\u5c3f\u75c5\u60a3\u8005\u306e\u9ad8\u8840\u7cd6\u72b6\u614b\u3092\u77ed\u671f\u9593\u3067\u5287\u7684\u306b\u6539\u5584\u3059\u308b\u3053\u3068\u304c\u5831\u544a\u3055\u308c\u3066\u3044\u308b\u304c\u3001\u9577\u671f\uff08\u6570\u5e74\uff5e\u4e00\u751f\u6daf\uff09\u306b\u308f\u305f\u308b\u52b9\u679c\u3068\u5b89\u5168\u6027\u306b\u3064\u3044\u3066\u7591\u554f\u8996\u3055\u308c\u3066\u3044\u308b\u3002\u307e\u305f\u3001\u5b9f\u9a13\u52d5\u7269\u3092\u7528\u3044\u305f\u7cd6\u8cea\u5236\u9650\u98df\u306e\u9577\u671f\u6442\u53d6\u306b\u3088\u308b\u52b9\u679c\u306b\u3064\u3044\u3066\u306f\u3001\u307b\u3068\u3093\u3069\u5831\u544a\u3055\u308c\u3066\u3044\u306a\u3044\u3002\u3053\u308c\u307e\u3067\u306b\u3001\u907a\u4f1d\u60272\u578b\u7cd6\u5c3f\u75c5\u30e2\u30c7\u30eb\u30e9\u30c3\u30c8\u3067\u3042\u308bGoto-Kakizaki (GK) \u30e9\u30c3\u30c8\u3092\u7528\u3044\u3066\u75c5\u614b\u3068\u5bff\u547d\u3092\u30e2\u30cb\u30bf\u30ea\u30f3\u30b0\u3057\u305f\u304c\u3001\u5bff\u547d\u5ef6\u9577\u52b9\u679c\u306f\u78ba\u8a8d\u51fa\u6765\u306a\u304b\u3063\u305f\u3002\u4eca\u5f8c\u306f\u5065\u5e38\u30e9\u30c3\u30c8\u3092\u7528\u3044\u3066\u540c\u69d8\u306b\u691c\u8a0e\u3057\u3066\u3044\u304f\u3002<\/p>\n\n\n\n

\uff13\uff0e\u98df\u54c1\u306e\u6a5f\u80fd\u6027\u6210\u5206\u306b\u95a2\u3059\u308b\u7814\u7a76<\/strong><\/p>\n\n\n\n

\u3000<\/strong>\u6297\u80a5\u6e80\u30fb\u6297\u7cd6\u5c3f\u75c5\u4f5c\u7528\u3092\u6709\u3059\u308b\u98df\u54c1\u7d20\u6750\u3084\u6a5f\u80fd\u6027\u6210\u5206\u306b\u3064\u3044\u3066\u7814\u7a76\u3057\u3066\u3044\u308b\u3002\u2460\u767a\u9175\u7384\u7c73\u62bd\u51fa\u7269\u3001\u2461\u5927\u8c46\u80da\u82bd\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u2462\u5375\u767d\u30bf\u30f3\u30d1\u30af\u8cea\u304a\u3088\u3073\u5375\u767d\u5206\u89e3\u7269\u3001\u2463\u9c39\u7bc0\u30bf\u30f3\u30d1\u30af\u8cea\u3001\u2464\u30ba\u30a4\u30ca\u4e7e\u71e5\u7c89\u672b\u3001\u2465\u305d\u306e\u4ed6\u3002<\/p>\n\n\n\n

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\u4ee3\u8868\u7684\u306a\u7814\u7a76\u696d\u7e3e<\/strong><\/p>\n<\/div>

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  • Ochiai M, et al. (2017) Comparison of anti-obesity effect between two types of syrup containing rare sugars in Wistar rats. J Nutr Sci Vitaminol 63: 207-212.<\/li>\n\n\n\n
  • Ochiai M, et al. (2017) Egg white hydrolysate can be a low-allergenic food material to suppress ectopic fat accumulation in rats fed an equicaloric diet. J Nutr Sci Vitaminol 63: 111-119.<\/li>\n\n\n\n
  • Hjossain A, et al. (2015) Rare sugar D-allulose: Potential role and therapeutic monitoring in maintaining obesity and type 2 diabetes mellitus. Pharmacl Ther 155: 49-59.<\/li>\n\n\n\n
  • Ochiai M, et al. (2015) Dietary protein derived dried bonito fish improves type-2 diabetes mellitus-induced bone frailty in Goto-Kakizaki rats. J Food Sci 80: H848-H856.<\/li>\n\n\n\n
  • Yamada T, et al. (2014) Dietary D-sorbose decreases serum insulin levels in growing Sprague-Dawley rats. J Nutr Sci Vitaminol 60: 297-299.<\/li>\n<\/ul>\n\n<\/div>
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    Research Area:\u3000<\/strong>Food Science<\/mark> \u3000\u3000\u3000\u3000
    <\/strong>Research Specialization:\u3000<\/strong>Food Nutrition<\/mark> \u3000
    <\/strong>Name:  <\/strong>MATSUO Tatsuhiro<\/mark><\/h2>\n\n\n\n
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    Keywords\uff1acarbohydrate and fat metabolism, nutrient, rare sugar<\/p>\n<\/div>\n\n\n\n

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    \uff11\uff0eStudy of functions of rare sugar D-allulose and rare sugar syrup<\/strong><\/h2>\n\n\n\n

    Recent Research<\/strong><\/h2>\n\n\n\n

    \u3000 d-Allulose (d-psicose), a C-3 epimer of d-fructose, is a rare sugar present in small quantities in nature. We have since demonstrated that d-allulose is a sweet carbohydrate that provides no energy and that it causes little toxic effect in rats. In addition, we suggested that d-allulose controls postprandial hyperglycemia in normal and diabetic animals. Thus, d-allulose may be useful in preventing obesity and diabetes in patients. On the other hand, rare sugar syrup (RSS) containing about 6% d-allulose has been sold as a less expensive sweetener in markets. We also showed that RSS reduced abdominal fat accumulation compared to high-fructose corn syrup.  We will study mechanisms about the functionality of d-allulose and other rare sugars except d-allulose in future.<\/p>\n\n\n\n

    \uff12\uff0eEffects of very low carbohydrate diet on body fat and metabolism\u3000<\/strong><\/h2>\n\n\n\n

    \u3000Recently, a very low carbohydrate diet (VLCD) become the topic through media as a diet cure of diabetes and have been already adopted at some hospitals. It is reported that the VLCD improves a hyperglycemia of the diabetic dramatically in a short term, but is doubted about effects and safety for long-term (several years – life). In addition, it is hardly reported the effect by the long-term intake of the VLCD using the laboratory animals. We have monitored the condition of rats and lifespan using the Goto-Kakizaki (GK) rats that were hereditary type-2 diabetes model rats, but were not able to confirm the life extension effect. We will examine the effects of VLCD using normal Wistar rats equally in future.<\/p>\n\n\n\n

    \uff13\uff0e<\/strong> <\/strong>Study of functional food ingredients<\/strong><\/h2>\n\n\n\n

    \u3000 Anti-obesity and anti-diabetes effects of functional food ingredients were studied as follows: (1) fermented brown rice, (2) soy germ protein, (3) egg white and egg white hydrolysate, (4) bonito fish protein, (5) dried Itea plant powder, (6) others.<\/p>\n\n\n\n

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    Publications<\/strong><\/p>\n<\/div>

    \"\"<\/figure><\/div>\n\n\n\n
      \n
    • Ochiai M, et al. (2017) Comparison of anti-obesity effect between two types of syrup containing rare sugars in Wistar rats.J Nutr Sci Vitaminol 63: 207-212.<\/li>\n\n\n\n
    • Ochiai M, et al. (2017) Egg white hydrolysate can be a low-allergenic food material to suppress ectopic fat accumulation in rats fed an equicaloric diet. J Nutr Sci Vitaminol 63: 111-119.<\/li>\n\n\n\n
    • Hjossain A, et al. (2015) Rare sugar D-allulose: Potential role and therapeutic monitoring in maintaining obesity and type 2 diabetes mellitus. Pharmacl Ther 155: 49-59.<\/li>\n\n\n\n
    • Ochiai M, et al. (2015) Dietary protein derived dried bonito fish improves type-2 diabetes mellitus-induced bone frailty in Goto-Kakizaki rats. J Food Sci 80, H848-H856.<\/li>\n\n\n\n
    • Yamada T, et al. (2014) Dietary D-sorbose decreases serum insulin levels in growing Sprague-Dawley rats. J Nutr Sci Vitaminol 60: 297-299.<\/li>\n<\/ul>\n\n<\/div><\/div>\n <\/div>","protected":false},"excerpt":{"rendered":"","protected":false},"author":1,"featured_media":10446,"menu_order":0,"comment_status":"open","ping_status":"open","template":"","meta":{"_coblocks_attr":"","_coblocks_dimensions":"","_coblocks_responsive_height":"","_coblocks_accordion_ie_support":"","ub_ctt_via":"","footnotes":""},"class_list":["post-3479","research","type-research","status-publish","has-post-thumbnail","hentry","research_keyword-240","research_keyword-237","research_keyword-135","research_keyword-239","research_keyword-238","research_category-217","center_category-258","center_category-259","sdgs_category-6","sdgs_category-5"],"_links":{"self":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/research\/3479","targetHints":{"allow":["GET"]}}],"collection":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/research"}],"about":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/types\/research"}],"author":[{"embeddable":true,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fcomments&post=3479"}],"version-history":[{"count":14,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/research\/3479\/revisions"}],"predecessor-version":[{"id":32733,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/research\/3479\/revisions\/32733"}],"wp:featuredmedia":[{"embeddable":true,"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=\/wp\/v2\/media\/10446"}],"wp:attachment":[{"href":"https:\/\/www.ag.kagawa-u.ac.jp\/index.php?rest_route=%2Fwp%2Fv2%2Fmedia&parent=3479"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}