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About us

 Secondary metabolites produced by plants and microorganisms exhibit diverse chemical structures and a wide range of biological activities that arise from this structural diversity. Therefore, many secondary metabolites (natural products) have been used as medicines, pesticides or drug candidates.
 In our laboratory, we aim to discover new natural products, novel medicinal seeds, and new agrochemical seeds by integrating the following four research pillars.

1. Development of screening systems for pharmaceutical and agricultural research
2. Development of methods to activate cryptic or silent gene clusters in microorganisms
3. Search for new natural products and bioactive compounds from collections of our plants and microorganisms, as well as from pathogenic microorganisms including Nocardia
4. Elucidation of the molecular mechanisms of new bioactive natural products and analysis of the biosynthetic gene clusters responsible for the production of new natural products
 
 Students in our laboratory are expected to grow as researchers with perspectives in both organic chemistry and biological sciences through their research activities.
Fig.1 Development of methods to activate cryptic or silent gene clusters in microorganisms

Fig.2 Isolated new natural products and their functional analysis

Members

・Faculty member
 Assist. Prof.
 Yasumasa Hara, Ph.D.
 ORCiD, researchmap

Students
 -graduate-
 1st year master’s student
  Yuka Tarui
  Tsubasa Horiuchi
  Miu Mori
  Bui Cong Tri (MEXT Scholarship Student)

 -undergraduate-
 4th year student
  Ai Kanagawa
  Mio Kuwahara
  So Yoshida
 3rd year student
  Yume Okawa
  Mao Kameda
  Riko Nakasone

Publications

Please see this page

Recruitment

 We welcome applications from postdoctoral researchers and graduate students, both within Japan and abroad, who possess a solid background in natural product structure elucidation.
 If you are interested in our research, please feel free to contact us by email.
 Contact to
 Assist. Prof. Yasumasa HARA
 hara.yasumasa[at]kagawa-u.ac.jp
  Please send e-mail replacing [at] with @.