Google Scholar search results for “”simplified analogue” natural products”, “”simplified analogues” natural products”, “”simplified-analog” natural products”, “”simplified analogs” natural products”, “”function-oriented-synthesis” natural products”, and “pseudo-natural-products”
Reviews published in 2019:
- Wang S, Dong G, Sheng C. Structural Simplification of Natural Products. Chem Rev. 2019 Mar 27;119(6):4180-4220. doi: 10.1021/acs.chemrev.8b00504. Epub 2019 Feb 7. PMID: 30730700.
- Abbasov ME, Alvariño R, Chaheine CM, Alonso E, Sánchez JA, Conner ML, Alfonso A, Jaspars M, Botana LM, Romo D. Simplified immunosuppressive and neuroprotective agents based on gracilin A. Nat Chem. 2019 Apr;11(4):342-350. doi: 10.1038/s41557-019-0230-0. Epub 2019 Mar 22. PMID: 30903037; PMCID: PMC6532426.
- Morão LG, Polaquini CR, Kopacz M, Torrezan GS, Ayusso GM, Dilarri G, Cavalca LB, Zielińska A, Scheffers DJ, Regasini LO, Ferreira H. A simplified curcumin targets the membrane of Bacillus subtilis. Microbiologyopen. 2019 Apr;8(4):e00683. doi: 10.1002/mbo3.683. Epub 2018 Jul 26. PMID: 30051597; PMCID: PMC6460283.
- Chany AC, Legros F, Haroun H, Kundu UK, Biletskyi B, Torlak S, Mathé-Allainmat M, Lebreton J, Macé A, Carboni B, Renoux B, Gosselin P, Dujardin G, Gaulon-Nourry C. Function-Oriented Synthesis toward Peloruside A Analogues. Org Lett. 2019 May 3;21(9):2988-2992. doi: 10.1021/acs.orglett.9b00413. Epub 2019 Mar 12. PMID: 30859834.
- Ashida Y, Yanagita RC, Kawanami Y, Okamura M, Dan S, Irie K. Synthesis, Conformation, and Biological Activities of a Des-A-Ring Analog of 18-Deoxy-Aplog-1, a Simplified Analog of Debromoaplysiatoxin. Heterocycles. 2019; 99(2):942-957. doi: 10.3987/COM-18-S(F)60.
- Pierrot D, Sinou V, Bun SS, Parzy D, Taudon N, Rodriguez J, Ollivier E, Bonne D. Design and synthesis of simplified speciophylline analogues and β-carbolines as active molecules against Plasmodium falciparum. Drug Dev Res. 2019 Feb;80(1):133-137. doi: 10.1002/ddr.21494. Epub 2018 Nov 29. PMID: 30499121.
- Qiao L, Duan Z, Chen Y, Luan Y, Gu Q, Liu YK, Li D. Aspergiolides A and B: Core Structural Establishment and Synthesis of Structural Analogues. J Org Chem. 2019 Apr 5;84(7):4451-4457. doi: 10.1021/acs.joc.8b03185. Epub 2019 Mar 21. PMID: 30865441.
- Henry JL, Wilson MR, Mulligan MP, Quinn TR, Sackett DL, Taylor RE. Synthesis, conformational preferences, and biological activity of conformational analogues of the microtubule-stabilizing agents, (−)-zampanolide and (−)-dactylolide. Medchemcomm. 2019 Apr 9;10(5):800-805. doi: 10.1039/c9md00164f. PMID: 31191870; PMCID: PMC6540953.
- Sosonyuk SE, Peshich A, Tutushkina AV, Khlevin DA, Lozinskaya NA, Gracheva YA, Glazunova VA, Osolodkin DI, Semenova MN, Semenov VV, Palyulin VA, Proskurnina MV, Shtil AA, Zefirov NS. Synthesis and cytotoxicity of novel simplified eleutherobin analogues as potential antitumour agents. Org Biomol Chem. 2019 Mar 6;17(10):2792-2797. doi: 10.1039/c8ob02915f. PMID: 30793716.
- Zacharova MK, Tulloch LB, Gould ER, Fraser AL, King EF, Menzies SK, Smith TK, Florence GJ. Structure-Based Design, Synthesis and Biological Evaluation of Bis-Tetrahydropyran Furan Acetogenin Mimics Targeting the Trypanosomatid F1 Component of ATP Synthase. European J Org Chem. 2019 Sep 1;2019(31-32):5434-5440. doi: 10.1002/ejoc.201900541. Epub 2019 May 29. PMID: 31598093; PMCID: PMC6774295.
- Evans DM, Hughes J, Jones LF, Murphy PJ, Falfushynska H, Horyn O, Sokolova IM, Christensen J, Coles SJ, Rzymski P. Elucidating cylindrospermopsin toxicity via synthetic analogues: An in vitro approach. Chemosphere. 2019 Nov;234:139-147. doi: 10.1016/j.chemosphere.2019.06.021. Epub 2019 Jun 10. PMID: 31207420.
- Monjas L, Fodran P, Kollback J, Cassani C, Olsson T, Genheden M, Larsson DGJ, Wallentin CJ. Synthesis and biological evaluation of truncated derivatives of abyssomicin C as antibacterial agents. Beilstein J Org Chem. 2019 Jul 2;15:1468-1474. doi: 10.3762/bjoc.15.147. PMID: 31354863; PMCID: PMC6633193.
- Kalmode HP, Patil SS, Handore KL, Athawale PR, Dandela R, Verma AK, Basu A, Reddy DS. Neural Anti‐Inflammatory Natural Product Periconianone A: Total Synthesis and Biological Evaluation. European J Org Chem. 2019;2019(13):2376-2381. doi: 10.1002/ejoc.201900048.
- Solinski AE, Scharnow AM, Fraboni AJ, Wuest WM. Synthetic Simplification of Carolacton Enables Chemical Genetic Studies in Streptococcus mutans. ACS Infect Dis. 2019 Aug 9;5(8):1480-1486. doi: 10.1021/acsinfecdis.9b00213. Epub 2019 Jun 25. PMID: 31243986; PMCID: PMC7169375.
- Ali R, Guan Y, Leveille AN, Vaughn E, Parelkar S, Thompson PR, Mattson AE. Synthesis and Anticancer Activity of Structure Simplified Naturally-Inspired Dimeric Chromenone Derivatives. European J Org Chem. 2019 Nov 10;2019(41):6917-6929. doi: 10.1002/ejoc.201901026. Epub 2019 Aug 27. PMID: 33828411; PMCID: PMC8023304.
- Tysoe CR, Caner S, Calvert MB, Win-Mason A, Brayer GD, Withers SG. Synthesis of montbretin A analogues yields potent competitive inhibitors of human pancreatic α-amylase. Chem Sci. 2019 Oct 18;10(48):11073-11077. doi: 10.1039/c9sc02610j. PMID: 32206255; PMCID: PMC7069248.