Simplified analogues of natural products published in 2015

Google Scholar and PubMed search results for “”simplified analogue” natural products”, “”simplified analogues” natural products”, “”simplified-analog” natural products”, “”simplified analogs” natural products”, “”function-oriented-synthesis” natural products”, and “pseudo-natural-products”. 

1. Pasqua AE, Ferrari FD, Crawford JJ, Whittingham WG, Marquez R. Synthesis of (+)-crocacin D and simplified bioactive analogues. Bioorg Med Chem. 2015 Mar 1;23(5):1062-8. doi: 10.1016/j.bmc.2015.01.008. Epub 2015 Jan 10. PMID: 25638500.
2. Schröder P, Förster T, Kleine S, Becker C, Richters A, Ziegler S, Rauh D, Kumar K, Waldmann H. Neuritogenic militarinone-inspired 4-hydroxypyridones target the stress pathway kinase MAP4K4. Angew Chem Int Ed Engl. 2015 Oct 12;54(42):12398-403. doi: 10.1002/anie.201501515. Epub 2015 Apr 23. PMID: 25908259.
3. Toneto Novaes LF, Martins Avila C, Pelizzaro-Rocha KJ, Vendramini-Costa DB, Pereira Dias M, Barbosa Trivella DB, Ernesto de Carvalho J, Ferreira-Halder CV, Pilli RA. (-)-Tarchonanthuslactone: Design of New Analogues, Evaluation of their Antiproliferative Activity on Cancer Cell Lines, and Preliminary Mechanistic Studies. ChemMedChem. 2015 Oct;10(10):1687-99. doi: 10.1002/cmdc.201500246. Epub 2015 Aug 25. PMID: 26305900.
4. Herkommer D, Dreisigacker S, Sergeev G, Sasse F, Gohlke H, Menche D. Design, synthesis, and biological evaluation of simplified side chain hybrids of the potent actin binding polyketides rhizopodin and bistramide. ChemMedChem. 2015 Mar;10(3):470-89. doi: 10.1002/cmdc.201402508. Epub 2015 Jan 29. PMID: 25641798.
5. Coe S, Pereira N, Geden JV, Clarkson GJ, Fox DJ, Napier RM, Neve P, Shipman M. Ring closing metathesis reactions of α-methylene-β-lactams: application to the synthesis of a simplified phyllostictine analogue with herbicidal activity. Org Biomol Chem. 2015 Jul 28;13(28):7655-63. doi: 10.1039/c5ob00890e. PMID: 26081012.
6. Park Y, Lee JK, Ryu JS. Synthesis of a cyclic analogue of Tuv N-methyl tubulysin. Synlett. 2015;26:1063–1068. doi: 10.1055/s-0034-1379900.
7. Nakaya T, Matsuda A, Ichikawa S. Design, synthesis and biological evaluation of 5′-C-piperidinyl-5′-O-aminoribosyluridines as potential antibacterial agents. Org Biomol Chem. 2015 Jul 28;13(28):7720-35. doi: 10.1039/c5ob01037c. Epub 2015 Jun 19. PMID: 26090936.
8. Ichikawa S, Yamaguchi M, Hsuan LS, Kato Y, Matsuda A. Carbacaprazamycins: Chemically Stable Analogues of the Caprazamycin Nucleoside Antibiotics. ACS Infect Dis. 2015 Apr 10;1(4):151-6. doi: 10.1021/id5000376. Epub 2015 Feb 19. PMID: 27622529.

9. Becker D, Kazmaier U. Synthesis of Simplified Halogenated Chondramide Derivatives with Strong Cytostatic Properties. 2015;2015(12):2591-2602. doi: 10.1002/ejoc.201403577. Epub 2015 Feb 9.

10. Hudnut AW, Trasolini NA, Hatch GFR 3rd, Armani AM. Biomechanical Analysis of Porcine Cartilage Elasticity. Ann Biomed Eng. 2019 Jan;47(1):202-212. doi: 10.1007/s10439-018-02133-9. Epub 2018 Sep 24. PMID: 30251031.
11. Hanaki Y, Yanagita RC, Sugahara T, Aida M, Tokuda H, Suzuki N, Irie K. Synthesis and biological activities of the amide derivative of aplog-1, a simplified analog of aplysiatoxin with anti-proliferative and cytotoxic activities. Biosci Biotechnol Biochem. 2015;79(6):888-95. doi: 10.1080/09168451.2014.1002452. Epub 2015 Jan 23. PMID: 25612633.
12. Matsumoto K, Suyama M, Fujita S, Moriwaki T, Sato Y, Aso Y, Muroshita S, Matsuo H, Monda K, Okuda K, Abe M, Fukunaga H, Kano A, Shindo M. Efficient Total Synthesis of Bongkrekic Acid and Apoptosis Inhibitory Activity of Its Analogues. Chemistry. 2015 Aug 3;21(32):11590-602. doi: 10.1002/chem.201501304. Epub 2015 Jun 30. PMID: 26126659.
13. Garcia-Rodriguez J, Mendiratta S, White MA, Xie XS, De Brabander JK. Synthesis and structure-activity studies of the V-ATPase inhibitor saliphenylhalamide (SaliPhe) and simplified analogs. Bioorg Med Chem Lett. 2015 Oct 15;25(20):4393-8. doi: 10.1016/j.bmcl.2015.09.021. Epub 2015 Sep 8. PMID: 26372654.
14. McNulty J, van den Berg S, Ma D, Tarade D, Joshi S, Church J. Antimitotic activity of structurally simplified biaryl analogs of the anticancer agents colchicine and combretastatin A4. Bioorg Med Chem Lett. 2015 Jan 1;25(1):117-21. doi: 10.1016/j.bmcl.2014.10.090. Epub 2014 Nov 11. PMID: 25466200.
15. Ni M, Esposito E, Raj VP, Muzi L, Zunino F, Zuco V, Cominetti D, Penco S, Dal Pozzo A. New macrocyclic analogs of the natural histone deacetylase inhibitor FK228; design, synthesis and preliminary biological evaluation. Bioorg Med Chem. 2015 Nov 1;23(21):6785-93. doi: 10.1016/j.bmc.2015.10.004. Epub 2015 Oct 9. PMID: 26481659.
16. Williams LK, Zhang X, Caner S, Tysoe C, Nguyen NT, Wicki J, Williams DE, Coleman J, McNeill JH, Yuen V, Andersen RJ, Withers SG, Brayer GD. The amylase inhibitor montbretin A reveals a new glycosidase inhibition motif. Nat Chem Biol. 2015 Sep;11(9):691-6. doi: 10.1038/nchembio.1865. Epub 2015 Jul 27. PMID: 26214255.